FIGHTING ORAL CANCER WITH MEDICINAL TURMERIC
The word ‘cancer’ often invokes the spectre of an inexorably lethal process;
Even today ‘cancer’ summons fear for those diagnosed with it, largely due to the deep-rooted stigma allied with this sensitive word, associated with an incorrigible and fatal disease.
A cancer diagnosis also affects family members and friends. The complex feelings and lifestyle changes caused by cancer and its treatment become as devastating for everyone around the patient as much as it affects the sufferer.
What Are The Statistics Of Oral Cancer In India?
India is dealing with a significantly high number of oral cancer patients.
Oral cancer is a foremost problem in the Indian subcontinent and it ranks amongst the top three types of cancer in the country.
The rate of oral cancer in India is high, which accounts for 20 per 100,000 population and makes for over 30% of all cancers in the country.
What Is Oral Cancer?
Oral cancer is cancer that develops in the tissues of the mouth or throat; most develop in the squamous cells found in your mouth, tongue, and lips.
Can Medicinal Turmeric Help Fight Oral Cancer?
Medicinal turmeric has been a torch bearer of anti-inflammatory and antioxidant actions.
Medicinal turmeric with the goodness of curcumin has antioxidant, anti-inflammatory, and potential chemotherapeutic properties. Curcumin the star polyphenol found in medicinal turmeric has showed its magical natural ability to be able to help in decreasing the incidence of oral squamous cell carcinoma.
Curcumin has pleiotropic activities derived from its complex chemistry as well as its capability to stimulate multiple nonlinear signalling pathways, as well as survival pathways such as those regulated by NF-kappaB, Akt, growth factors, and cytoprotective pathways reliant on on Nrf2 as well metastatic and angiogenic pathways, which shows it’s a good choice to naturally combat oral cancer.
Anti- Inflammatory Effects On Oral Cancer
Curcumin also overwhelms the inflammatory response which constrains the induction of COX-2, iNOS and production of cytokines such as interferon-c, due to the suppression of Janus kinase (JAK) –STAT nonlinear signalling cascade & thwarting the oral cancer from spreading.
Curcumin scavenges free radicals and hydrogen donors and exhibits both pro and antioxidant activity.
Curcumin in medicinal turmeric also binds metals, particularly iron and copper, and can function as an iron chelator & it is sufficient for its chemotherapeutic and chemo-preventive activity. ROS(Reactive oxygen species), such as superoxide anions and hydroxyl radicals play an important role in carcinogenesis, as curcumin in medicinal turmeric has the ability to rummage superoxide anion radicals and hydroxyl radicals and it also possess pro-oxidant activity and has antioxidant effects.
Restraint Of Cyclooxygenase Transcription
Curcumin has anti-inflammatory and antioxidant activities which results in the inhibition of lipo-oxygenase and cyclo-oxygenase activities that can induce inflammation especially in the one suffering from oral cancer.
It has been known that curcumin in medicinal turmeric has endless ability to hinder cyclooxygenase (COX) enzyme activity in human platelets. COX-2 is overexpressed in the cancer of head and neck tumours. Curcumin in medicinal turmeric impedes stimulation of COX-2 gene expression in oral and colon epithelial cells. The inhibitors of COX-2, which constrains the catalytic activity of the COX enzyme, such as curcumin, decline the expression of COX-2 at transcriptional level.
The gene inhibition of COX-2 is the chief anti-inflammatory activity of curcumin found in the natural medicinal turmeric.
Inhibition Of Carcinogenesis After Application Of Curcumin
Application of curcumin thrice weekly to the buckle pouch of Syrian golden hamsters causes inhibition of DMBA-induced oral carcinogenesis.
Inhibition Of Oral Cancer In Cell Cycle
The anticancer effects of curcumin cause trepidations in cell cycle progression.
Curcumin found in medicinal turmeric affects the cell-to-cell union proteins, like
3. Hinders the production of cytokines related to tumour growth
4. Diminishing the expression of membrane surface molecules that play a role in cellular adhesion
5. Through complex nonlinear pathways
Curcumin in medicinal turmeric expresses anti-oxidant, anti-inflammatory, anti-antigenic, anti-mitotic, and anti-metastatic activities.
In effect, Curcumin appears to be a promising molecule for the prevention and treatment of cancer in humans.
Similarly, a promising supplement for oral cancer which sure is the rising star is Oropharynim from Bagdara Farms.
It has innumerable anti-oxidant and anti-viral properties; it is a natural Anti-septic, Anti-biotic, Anti-inflammatory.
Oropharynim prevents metastasis, it is super in:
1. Chemo-protective ability,
2. Has a plethora of Anti-Cancer,
4. Immune-modulatory properties
5. It is also a Natural Analgesic
What else do you need in a product! It is sure to put you back on the road to recovery and you will emerge as a winner with great health as a prize for you and your family.