chronic stress with curcumin
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Mood and anxiety disorders are very common these days due to a hectic and stressful lifestyle. Mood disorders can be characterized by regular mood disturbances that include depression, elevated moods, and mood swings. On the other hand, anxiety disorders can be described as an overwhelming fear, concern, or worry about something so much so that it interferes with daily life. Now the million-dollar question is what are the factors that are responsible for this? The most prevalent answer found after many case studies and research is chronic stress. Interestingly, not all who undergo stress have these psychiatric disorders.

Chronic Social Defeat Stress- An Experiment

A very interesting experiment called the chronic social defeat stress was done on 129/ SvEv mice. This is a strain of mice that is highly susceptible to this type of stress. Findings from the CSDS studies indicate that susceptibility to stress and resilience are under the control of distinct changes in the signal transduction pathways, gene transcription, and neurophysiological activity.

Going as per the experiment, five days prior to the test, standard laboratory chow was replaced by an 18% protein chow diet which had 1.5% curcumin. Along with the chronic social defeat stress, some other tests like social interaction tests, elevated plus maze, open field, and acute restraint stress were also done. In the elevated plus-maze there is an apparatus which consists of two open arms and two arms closed by walls, that are connected by a central platform 50 cm above the ground. The mice were then individually placed in the center platform facing an open arm and were given 5 min to explore the maze under the low light conditions. A camera kept overhead recorded behavior for scoring later by an observer blind to the treatment group.  Measurements of the levels of Plasma IL-6, cortisone, and brain IL-6 were also carried out.

The end result says curcumin is the answer to bring down stress. Curcumin is a biologically active polyphenolic compound found in the turmeric plant called Curcuma longa. It is commonly used as a popular spice in East Asian and Indian countries.

chronic stress

  • Firstly, a large number of mice fed with high proportions of curcumin exhibited resilience to stress.
  • Secondly, It was also observed that curcumin helps to regulate the inflammatory response to stress.
  • Lastly, the results of the experiment indicated that curcumin which is administered during stress exposure prevents the development of anxiety-like behavior.

Curcumin is also known to reduce the symptoms of depression. CSDS can activate the IKK0 NFkB signaling pathway in the periphery and the brain which leads to the development of stress-induced depression and anxiety-like behavior. Curcumin, in turn, is known to inhibit this pathway as well as regulating the inflammatory response.

Moreover, treatment with curcumin is a safe and effective therapy for the prevention of social withdrawal and other symptoms of anxiety in individuals. It comes without any side effects which is the best part of curcumin intake. One must keep in mind that taking the best quality of curcumin is very important. Consumption of the regular over the counter curcumin will not be as effective.

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Clinical Trial & Our Product

Since health care & medicine is an industry, formulations are controlled through intellectual property rights denying easy access to common people and maintaining the buoyancy for the interest holders. Formula’s can be patented and that covers business interests that drive innovations these days.

So instead of conducting trials on the raw root, almost all companies promote clinically tested formulations of extracts to make it appear better then how the phytochemical was in its original state. Its like extracting an important organ from the body and then putting it on support system, expecting it to perform better in insolation then how it could perform when in it was in its natural form. The truth is, that the best way to consume a plant based medicine is in its raw form. Curcumin is one of the active ingredients in the root Curcuma Longa.

Since its more important to know what your food ate then what you ate, its important to know that the supplements you are using based on curcumin has curcumin from a gene modified variety of curcuma longa which suffers from an imbalance of every other mineral. You see a plant also behaves how a human body behaves when it is injected with steroids to gain muscle mass for body building purpose. The plants have higher levels of curcumin but all other secondary minerals found along curcumin in the plant get compromised as the plant can not feed all nutritions equally when it is designed to feed most of its nutrition towards developing higher levels of curcumin. It has severe side effects on the health of the plant and apparently on the people consuming such plants or extracts coming from these plants. However marketing and promotions have evolved to divert attention very wisely.

An extract of any herb can never be stored in its original state and hence needs base agents, preservatives which hardly leave it how it must be. We believe that access to medicine and healthcare is a basic right of every human and animal living on planet earth. Hence we do not first extract and then add preservatives or agents like pepperine to make the extract bio-available. This is the reason we never patent any of our products. We instead hand process the whole root we cultivate in our farms and share it with the people under different brand names for different health conditions based on the concentration of minerals present at testing. You can also buy the seed from us and cultivate it but it will certainly not be as potent as you get from us.

How potent is the active ingredient in the plant depends on the quality of seed, soil, water and environment. Our products work far better then most of the curcumin based supplements globally being used for Therapeutic benefits.

We do not intend to formulate or patent our products. So instead of choosing a supplement with an extract, choose wisely and go for the best and not the Cheapest.

All our products are cultivated, harvested, hand processed and distributed directly from our own farms to ensure that people who depend on our products for their acute and chronic problems get consistent supply of highest quality, ultra premium, medicinal grade, Non-GMO, Indigenous, Naturally enriched with curcumin, Wild Strand curcuma longa powder for therapeutic benefits. We cultivate this in the middle of a national park which happens to be the best breeding ground for Bengal tigers in India called Bandhavgarh.